From Hartford:
Take Route 2 east to Route 11, follow to the end. At the end of the exit ramp turn left on to Route 82. At the light (Salem Four Corners) turn right onto Route 85. Continue south for approximately 12 miles into New London. Turn right at traffic light onto Colman Street (Route 213).

At the end of Colman, turn right onto Bank Street, then an immediate left onto Lee Avenue. At the end of Lee, turn right onto Ocean Avenue. Go through one stop light, then turn left at the fourth street onto Faire Harbour Place (for Same-Day Surgery, Emergency Room, Community Cancer Center and Physicians Office Suites, patient drop-off area will be on the right). At stop sign turn right on Montauk Avenue. The Ambulatory Care Center and Main Hospital Entrances are on the right.

From Worcester or Norwich:
Take I-395 south to exit 78 to Route 32. Follow Route 32 into downtown New London where it becomes Eugene O'Neill Drive and then Green Street. Turn left at the end onto Tilley Street and a right onto Bank Street at the fire station. Follow Bank Street to the fourth stop light and turn left at Shalett's Cleaners onto Montauk Avenue. The Ambulatory Care Center and Main Hospital Entrances will be on the right, approximately one mile.

From New York and New Haven:
Take I-95 north to exit 82A, Frontage Road. Keep right and follow to Colman Street exit (Route 1 south). Turn left onto Colman Street and follow second paragraph of the directions From Hartford.

From Providence and Boston:
Take I-95 south to exit 83, Frontage Road. Take Colman Street exit and turn left onto Colman Street. Follow second paragraph of the directions From Hartford.